Select the most appropriate option to fill in the blank.

He didn't tell me anything ______ that he needed some money.

except

The most appropriate option to fill in the blank is except.

The word "except" means "excluding." This is the most appropriate word because it accurately describes how the speaker is saying that the person did not tell them anything, except for the fact that they needed some money.

The other options are not as appropriate.

• Despite means "even though." This does not make sense in the context of the sentence, because the speaker is not saying that the person did not tell them anything, despite the fact that they needed some money.
• In spite of means "even though." This is similar to the word "despite," and it does not make sense in the context of the sentence for the same reason.
• Though means "although." This does not make sense in the context of the sentence, because the speaker is not saying that the person did not tell them anything, although they needed some money.