Select the appropriate antonym for the underlined word.

Social justice has been one of the cherished goals of the makers of our Constitution.

despised

The correct answer is option 4. despised.

In the context of the sentence, "cherished" is used to convey the idea that social justice is highly valued and deeply appreciated by the makers of the Constitution. They hold it in high regard and consider it to be an important and treasured goal. 

The antonym "despised" means to feel contempt or a strong dislike for something. Therefore, in this context, "despised" would convey the opposite meaning. If social justice were despised by the makers of the Constitution, it would mean they held it in low regard or had a negative attitude towards it, which contradicts the sentiment expressed in the sentence.