Target Exam

CUET

Subject

Biology

Chapter

Molecular Basis of Inheritance

Question:

In which type of RNA, methyl guanosine triphosphate capping is added to 5'-end?

Options:

rRNA

mRNA

tRNA

hnRNA

Correct Answer:

hnRNA

Explanation:

The correct answer is Option (4) → hnRNA 

In eukaryotes, there are two additional complexities – (i) There are at least three RNA polymerases in the nucleus (in addition to the RNA polymerase found in the organelles). There is a clear cut division of labour. The RNA polymerase I transcribes rRNAs (28S, 18S, and 5.8S), whereas the RNA polymerase III is responsible for transcription of tRNA, 5srRNA, and snRNAs (small nuclear RNAs). The RNA polymerase II transcribes precursor of mRNA, the heterogeneous nuclear RNA (hnRNA).

(ii) The second complexity is that the primary transcripts contain both the exons and the introns and are non-functional. Hence, it is subjected to a process called splicing where the introns are removed and exons are joined in a defined order. hnRNA undergoes additional processing called as capping and tailing. In capping an unusual nucleotide (methyl guanosine triphosphate) is added to the 5'-end of hnRNA. In tailing, adenylate residues (200-300) are added at 3'-end (polyadenylation) in a template independent manner. It is the fully processed hnRNA, now called mRNA, that is transported out of the nucleus for translation.