T-lymphocytes first mature in which of the following?
Answer & explanation
Correct answer: option 4
The primary lymphoid organs
are bone marrow and thymus where immature lymphocytes differentiate
into antigen-sensitive lymphocytes. After maturation the
lymphocytes migrate to secondary lymphoid organs like spleen,
lymph nodes, tonsils, Peyer’s patches of small intestine and
appendix. The secondary lymphoid organs provide the sites for
interaction of lymphocytes with the antigen, which then proliferate
to become effector cells.