The correct answer is Option (4) → despondent
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Melancholy (Noun/Adjective) means a feeling of pensive sadness, typically with no obvious cause.
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Despondent (Adjective) means in low spirits from loss of hope or courage; feeling or showing profound hopelessness. It is the closest synonym to deep sadness or gloom.
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Cheerful is an antonym.
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Boorish means rough and bad-mannered.
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Benign means gentle and kind, or not harmful (of a disease).
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