Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Principles of Inheritance and Variation

Question:

Which among the following is not X-linked recessive disease ?

Options:

Haemophilia .

colour blindness.

Beta thalassemia .

All of these .

Correct Answer:

Beta thalassemia .

Explanation:

The correct answer is Option (3) -Beta thalassemia .

Among the options provided, "Beta thalassemia" is not an X-linked recessive disease.

Haemophilia and color blindness are examples of X-linked recessive disorders, meaning the genes responsible for these conditions are located on the X chromosome. Inheritance of these disorders follows an X-linked pattern, where females (XX) need two copies of the mutant gene to express the disorder, while males (XY) only need one copy of the mutant gene to manifest the condition.

Beta thalassemia, on the other hand, is not an X-linked recessive disease. It is an autosomal recessive disorder caused by mutations in genes located on autosomal chromosomes (non-sex chromosomes). In the case of beta thalassemia, mutations occur in the genes related to the production of hemoglobin, which is located on autosomal chromosomes (chromosome 11). Both males and females inherit autosomal recessive disorders in a similar manner, requiring two copies of the mutated gene (one from each parent) to express the disorder.

Therefore, among the listed options, "Beta thalassemia" is not an X-linked recessive disease; it is an autosomal recessive disorder.