Match List - I with List - II.

Choose the correct answer from the options given below:

(A)-(II), (B)-(III), (C)-(IV), (D)-(I)

The correct answer is Option (4) → (A)-(II), (B)-(III), (C)-(IV), (D)-(I)

A. Vaccine safety: Transgenic mice are being developed for use in testing the safety of vaccines before they are used on humans. Transgenic mice are being used to test the safety of the polio vaccine. If successful and found to be reliable, they could replace the use of monkeys to test the safety of batches of the vaccine.

B. PCR (Polymerase Chain Reaction) is relevant for molecular Diagnosis, as PCR is a key technique in diagnosing diseases at the molecular level by amplifying DNA sequences.

C. Genetic modification has enabled the enhancement of the nutritional value of certain foods. One example is golden rice, which has been genetically modified to synthesize beta-carotene, a precursor of vitamin A. This modification has increased the nutritional content of the rice and can help combat vitamin A deficiency in regions where rice is a staple food.

D. If a person is born with a hereditary disease,  a corrective therapy can be taken for such a disease is gene therapy. Gene therapy is a collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo. Here genes are inserted into a person’s cells and tissues to treat a disease.