Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Biotechnology and its Applications

Question:
Which among the following is a permanent cure for ADA( adenosine deaminase ) deficiency ?
Options:
By bone marrow transplantation.
By enzyme replacement therapy.
Introduction of gene isolate from marrow cells producing ADA into early embryonic cells.
None of these.
Correct Answer:
Introduction of gene isolate from marrow cells producing ADA into early embryonic cells.
Explanation:
The disorder is caused due to the deletion of the gene for adenosine deaminase. In some children ADA deficiency can be cured by bone marrow transplantation; it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But the problem with both of these approaches that they are not completely curative.. However, if the gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stages, it could be a permanent cure.