Practicing Success

Target Exam

CUET

Subject

Biology

Chapter

Human Health and Disease

Question:

Read the following passage and answer the following question.
Cancer is one of the most dreaded diseases of human beings and is a major cause of death all over the globe. More than a million Indians suffer from cancer and a large number of them die from it annually. The mechanisms that underlie development of cancer or oncogenic transformation of cells, its treatment and control have been some of the most intense areas of research in biology and medicine. . Normal cells show a property called contact inhibition by virtue of which contact with other cells inhibits their uncontrolled growth. Cancer cells appears to have lost this property. As a result of this, cancerous cells just continue to divide giving rise to masses of cells called tumors. Transformation of normal cells into cancerous cells may be induced by carcinogens. Radiations cause DNA damage leading to neoplastic transformation.Cancer causing viruses called oncogenic viruses have genes called viral oncogenes. Cancer detection is based on biopsy and histopathological studies of the tissue and blood and bone marrow tests for increased cell counts in the case of leukemias. Techniques like radiography, CT and MRI are very useful to detect cancers of the internal organs. The common approaches for treatment of cancer are surgery, radiation therapy and immunotherapy.

Which carcinogen present in tobacco smoke is responsible for lung cancer?(Question 5)

Options:

Physical Carcinogen

Chemical Carcinogen

Biological Carcinogen

All of the above

Correct Answer:

Chemical Carcinogen

Explanation:

The correct answer is Option (2) –Chemical Carcinogen

Transformation of normal cells into cancerous neoplastic cells may be induced by physical, chemical or biological agents. These agents are called carcinogens. Ionising radiations like X-rays and gamma rays and non-ionizing radiations like UV cause DNA damage leading to neoplastic transformation. The chemical carcinogens present in tobacco smoke have been identified as a major cause of lung cancer.

Tobacco has been used by human beings for more than 400 years. It is smoked, chewed or used as a snuff. Tobacco contains a large number of chemical substances including nicotine, an alkaloid. Nicotine stimulates adrenal gland to release adrenaline and nor-adrenaline into blood circulation, both of which raise blood pressure and increase heart rate. Smoking is associated with increased incidence of cancers of lung, urinary bladder and throat, bronchitis, emphysema, coronary heart disease, gastric ulcer, etc.