Select the most appropriate one-word substitution for the given group of words.

An act of Murdering someone

Homicide

The most appropriate one-word substitution for "an act of murdering someone" is homicide.

• Homicide is the killing of one person by another.
• Infanticide is the murder of a child, especially a newborn.
• Fratricide is the murder of one's brother or sister.
• Suicide is the act of killing oneself.

The word homicide comes from the Latin words "homo," meaning "human," and "caedere," meaning "to kill." Homicide is a legal term that refers to the killing of one person by another, regardless of the intent of the killer.