Practicing Success
Read the given paragraph and answer the question: Humans have 23 pairs of chromosomes. 22 pairs are exactly same in both males and females; these are the autosomes. A pair of X-chromosome are present in the female, whereas the presence of an X and Y chromosome are determinant of the male characteristic. A number of disorders in human beings have been found to be associated with the inheritance of changed or altered genes or chromosomes. Broadly, genetic disorder may be grouped into two categories disorders and Chromosomal disorders. |
A disorder caused due to absence of one of the 'X' chromosome is - |
Turner's Syndrome Down's Syndrome Klinefelter's Syndrome Thalassemia |
Turner's Syndrome |
The correct answer is Option (1)- Turner's Syndrome Turner's syndrome - AA + XO: Turner's syndrome is caused due to the absence of one of the X chromosomes, i.e., 45 with X0, Such females are sterile as ovaries are rudimentary besides other features including lack of other secondary sexual characters. Down's syndrome - Trisomy: Down syndrome results from an extra copy of chromosome 21, known as trisomy 21, where there are three copies of chromosome 21 instead of the usual two. Klinefelter's Syndrome - Karyotype of 47 ,XXY : Klinefelter's Syndrome is characterized by the presence of an extra X chromosome in males, resulting in a karyotype of 47,XXY. Thalassemia - Mendelian Disease : Thalassemia refers to a group of inherited blood disorders caused by mutations in the genes that produce hemoglobin and is considered a Mendelian genetic disorder due to its inheritance patterns. |