The most appropriate synonym of the word "misfortune" is calamity.
- Misfortune is defined as "an unfortunate event causing great distress or loss."
- Calamity is defined as "a very serious and unfortunate event causing great damage or suffering."
- Benefit is defined as "something that is useful or helpful."
- Support is defined as "the act of providing assistance or encouragement."
- Miracle is defined as "an extraordinary event manifesting divine intervention in human affairs."
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