An individual with 44+XO karyotype is suffering from which of the following disorder?

Turner's Syndrome

The correct answer is Option (2) → Turner's Syndrome

Turner’s Syndrome : Such a disorder is caused due to the absence of one of the X chromosomes, i.e., 45 with XO, Such females are sterile as ovaries are rudimentary besides other features including lack of other secondary sexual characters.

Down’s Syndrome : The cause of this genetic disorder is the presence of an additional copy of the chromosome number 21 (trisomy of 21). This disorder was first described by Langdon Down (1866). The affected individual is short statured with small round head, furrowed tongue and partially open mouth. Palm is broad with characteristic palm crease. Physical, psychomotor and mental development is retarded.

Klinefelter’s Syndrome : This genetic disorder is also caused due to the presence of an additional copy of Xchromosome resulting into a karyotype of 47, 44+XXY. Such an individual has overall masculine development, however, the feminine development (development of breast, i.e., Gynaecomastia) is also expressed . Such individuals are sterile.

Haemophilia : This sex linked recessive disease, which shows its transmission from unaffected carrier female to some of the male progeny has been widely studied. In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected. Due to this, in an affected individual a simple cut will result in non-stop bleeding.