Identify the statements which hold true for transgenic animals.

(A) Transgenic animals can be used to study vaccine safety.
(B) Over 95% of transgenic animals are mice
(C) Transgenic animals cannot be used to study human diseases
(D) Transgenic animal possess and express forgein gene

Choose the correct answer from the options given below:

(A), (B) and (D) Only

The correct answer is Option (2) → (A), (B) and (D) Only

Animals that have had their DNA manipulated to possess and express an extra (foreign) gene are known as transgenic animals. Transgenic rats, rabbits, pigs, sheep, cows and fish have been produced, although over 95 per cent of all existing transgenic animals are mice.

Vaccine safety: Transgenic mice are being developed for use in testing the safety of vaccines before they are used on humans. Transgenic mice are being used to test the safety of the polio vaccine. If successful and found to be reliable, they could replace the use of monkeys to test the safety of batches of the vaccine.

Study of disease: Many transgenic animals are designed to increase our understanding of how genes contribute to the development of disease. These are specially made to serve as models for human diseases so that investigation of new treatments for diseases is made possible. Today transgenic models exist for many human diseases such as cancer, cystic fibrosis, rheumatoid arthritis and Alzheimer’s.