During allergic reactions, which of the following are secreted?
(A) Histamines
(B) Interferons
(C) Serotonin
(D) Pyrogens
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 4
The correct answer is Option (4) → (A) and (C) only
(A) Histamines — Correct. Mast cells release histamine when an allergen binds to the IgE antibodies on them. It causes sneezing, watery eyes and a running nose.
(B) Interferons — Incorrect. Interferons are proteins made by virus-infected cells to protect other cells from viral infection. They are not part of the allergic reaction.
(C) Serotonin — Correct. Serotonin is released from the mast cells along with histamine.
(D) Pyrogens — Incorrect. Pyrogens are substances that cause fever. They are not the chemicals behind an allergy.
Note: The same question was also asked in CUET (UG) 2025 on 03-06-2025 (Slot 1).
NCERT Extract:
Allergies – “The exaggerated response of the immune system to certain antigens present in the environment is called allergy. The substances to which such an immune response is produced are called allergens. The antibodies produced to these are of IgE type. Common examples of allergens are mites in dust, pollens, animal dander, etc. Symptoms of allergic reactions include sneezing, watery eyes, running nose and difficulty in breathing. Allergy is due to the release of chemicals like histamine and serotonin from the mast cells.”