The correct homophone to fill in the blank is: Cell
The sentence would be: "A cell always renews by itself."
- Cell: In biology, a cell is the basic structural and functional unit of all living organisms. It's capable of self-renewal and is a suitable fit for the context provided.
The other options:
- Sell: This refers to the action of selling, which doesn't fit the context of self-renewal.
- Shall: This is a modal verb used to indicate a future action or possibility. It doesn't make sense in the context provided.
- Sale: This refers to the exchange of goods for money, and it doesn't fit the context of self-renewal.
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