Which of the following produce antibodies?

B-lymphocytes

The correct answer is Option (1) - B-lymphocytes

The primary and secondary immune responses are carried out with the help of two special types of lymphocytes present in our blood, i.e., B-lymphocytes and T-lymphocytes. The B-lymphocytes produce an army of proteins in response to pathogens into our blood to fight with them. These proteins are called antibodies. The T-cells themselves do not secrete antibodies but help B cells to produce them.

Humoral immunity is a type of immune response that involves the production of antibodies by B-lymphocytes (B-cells) to defend against extracellular pathogens, such as bacteria and viruses that are circulating in bodily fluids like blood and lymph.