Steps of replication of retrovirus (HIV) in the host cell are given below. Arrange the steps in correct sequence.
(A) Viral RNA is introduced in host cell
(B) New viruses with new RNA are produced
(C) Viral DNA is produced by reverse transcription
(D) Viral DNA incorporates into host genome
(E) Virus infects the normal cell
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → (E), (A), (C), (D), (B)
The virus infects a cell (E), its RNA enters (A), reverse transcriptase makes viral DNA (C), the DNA joins the host genome (D), and new viruses are released (B).
Note: A similar question was also asked in CUET (UG) 2026 on 29-05-2026 (Slot 1), on 24-05-2026 (Slot 2), on 14-05-2026 (Slot 2) and on 14-05-2026 (Slot 1).
NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”