The most appropriate antonym of the word impure is sterile.
- Impure means "not pure; mixed with something else."
- Sterile means "free from living microorganisms; germ-free."
The other words do not have the same meaning as impure, so they are not its antonyms.
- Contaminated means "made impure by the introduction of something harmful or dirty."
- Segregated means "kept separate from others, especially on the basis of race, class, or gender."
- Concentrated means "having a high proportion of a particular substance or element."
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