Select the most appropriate one-word substitution for the given words.

To come to an end

expire

The most appropriate one-word substitution for the given words is expire.

• Initiate means to begin or start something.
• Exhale means to breathe out.
• Inspire means to motivate or encourage someone.
• Expire means to come to an end or die.

The word expire is the best fit because it specifically means to come to an end. It can be used to refer to the end of a life, a contract, or a period of time.