Select the most appropriate one-word substitution for the given group of words. 

An act of speaking wrong and derogatory about God or sacred things.

Blasphemy

The most appropriate one-word substitution for an act of speaking wrong and derogatory about God or sacred things is blasphemy.

• Somnambulist is a person who walks in their sleep.
• Philatelist is a person who collects stamps.
• Herbarium is a collection of dried plants.

The word blasphemy is derived from the Greek words blasphemein, meaning "to speak evil of", and theos, meaning "god". It is the act of speaking or writing with disrespect for God or sacred things. Blasphemy can be verbal or written, and it can be intentional or unintentional.