Select the option that can be used as a one-word substitute for the given group of words.

Evoking a keen sense of sadness or regret

Poignant

The word that can be used as a one-word substitute for "evoking a keen sense of sadness or regret" is poignant.

• Pungent means having a sharp, strong, or biting taste or smell.
• Poignant means evoking a keen sense of sadness or regret.
• Impactful means having a strong or significant effect.
• Unaffecting means having no effect or impact.

Poignant is the most appropriate word for the given group of words because it specifically refers to something that evokes a strong feeling of sadness or regret. It is derived from the Latin word pungere, meaning "to prick."