What will the isoelctric point (pI), if pK1=3.42 and pK2=11.54?
Answer & explanation
Correct answer: option 3
The correct answer is option 3. 7.48.
To calculate the isoelectric point (pI) of an amino acid with two pKa values, you can use the formula:
\(\text{pI} = \frac{\text{pKa1} + \text{pKa2}}{2} \)
Given:
\(pK_1 = 3.42\)
\(pK_2 = 11.54\)
\(\text{pI} = \frac{3.42 + 11.54}{2} = \frac{14.96}{2} = 7.48 \)
Therefore, the isoelectric point \((pI\)) is 7.48.
So, the correct answer is 7.48.