Low level of Thyroxine hormone is correlated with

The correct answer is Option (1) → Iodine deficiency

Thyroxine (T₄) is a thyroid hormone produced by the thyroid gland. Its synthesis requires iodine as an essential component—each thyroxine molecule contains four iodine atoms.

• A low level of thyroxine (hypothyroidism) is directly correlated with iodine deficiency, which leads to reduced hormone production. This is a common cause of goiter and cretinism in iodine-deficient regions.
• The other deficiencies are not directly correlated with low thyroxine:
• Vitamin A deficiency: Affects vision, immunity, and growth.
• Vitamin C deficiency: Causes scurvy.
• Vitamin D deficiency: Leads to rickets or osteomalacia.

Thus, the correct answer is Iodine deficiency.