Which one of the following hormones stimulates Sertoli cells to help in the process of spermatogenesis?
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → FSH
Spermatogenesis starts at puberty. The hypothalamic hormone GnRH makes the anterior pituitary release two gonadotropins, LH and FSH.
(1) FSH — Correct. FSH (follicle stimulating hormone) acts on the Sertoli cells. These cells then secrete factors that help the process of spermiogenesis.
(2) LH — Incorrect. LH (luteinising hormone) acts on the Leydig cells and makes them secrete androgens. The androgens in turn stimulate spermatogenesis. LH does not act on the Sertoli cells.
(3) Progesterone — Incorrect. This is a female hormone, made by the corpus luteum and the placenta. It maintains the uterine lining during pregnancy.
(4) hPL — Incorrect. Human placental lactogen is made by the placenta during pregnancy. It has no role in spermatogenesis.
NCERT Extract:
Gametogenesis – “… The increased levels of GnRH then acts at the anterior pituitary gland and stimulates secretion of two gonadotropins – luteinising hormone (LH) and follicle stimulating hormone (FSH). LH acts at the Leydig cells and stimulates synthesis and secretion of androgens. Androgens, in turn, stimulate the process of spermatogenesis. FSH acts on the Sertoli cells and stimulates secretion of some factors which help in the process of spermiogenesis.”