Arrange the stages of HIV infection in humans sequentially.
A. Introduction of viral DNA in the cell
B. Production of multiple viruses
C. Infection of human cell by virus
D. Incorporation of viral DNA into host genome
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 2
The correct answer is Option (2) → C, A, D, B
C. Infection of human cell by virus — first. HIV enters a macrophage (and later helper T-lymphocytes).
A. Introduction of viral DNA in the cell — second. Inside the cell the viral RNA is copied into viral DNA by reverse transcriptase.
D. Incorporation of viral DNA into host genome — third. The viral DNA joins the host cell's DNA and directs the cell to make virus particles.
B. Production of multiple viruses — last. The infected cell keeps releasing new viruses, which attack more helper T-cells, so the immunity of the person falls.
NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”