Match List-I with List-II:

Choose the correct answer from the options given below:

(A)-(IV), (B)-(I), (C)-(III), (D-(II)

The correct answer is Option (4) → (A)-(IV), (B)-(I), (C)-(III), (D-(II)

A. Thalassemia : This is also an autosome-linked recessive blood disease transmitted from parents to the offspring when both the partners are unaffected carrier for the gene (or heterozygous). The defect could be due to either mutation or deletion which ultimately results in reduced rate of synthesis of one of the globin chains (α and β chains) that make up haemoglobin.

B. Klinefelter’s Syndrome : This genetic disorder is also caused due to the presence of an additional copy of Xchromosome resulting into a karyotype of 47, 44+XXY. Such an individual has overall masculine development, however, the feminine development (development of breast, i.e., Gynaecomastia) is also expressed . Such individuals are sterile.

C. Turner’s Syndrome : Such a disorder is caused due to the absence of one of the X chromosomes, i.e., 45 with XO, Such females are sterile as ovaries are rudimentary besides other features including lack of other secondary sexual characters.

D. Colour blindness is a genetic disorder that is inherited in an X-linked recessive pattern. This means that the gene responsible for colour vision is located on the X chromosome, and males have only one X chromosome, while females have two X chromosomes.