Match the Column I with Column II :

A-4,B-3,C-2,D-1

The correct answer is Option (3) – A-4,B-3,C-2,D-1

Explanation:

A. Rosie - Transgenic cow: 

In 1997, scientists achieved a significant breakthrough by creating the first transgenic cow named Rosie. This cow was genetically modified to produce human protein-enriched milk, specifically containing human alpha-lactalbumin.The milk produced by Rosie had a significantly higher concentration of human alpha-lactalbumin compared to regular cow's milk(2.4 grams per litre).

B. α-1-antitrypsin - Emphysema: Medicines required to treat certain human diseases can contain biological products, but such products are often expensive to make. Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA (or genes) which codes for a particular product such as human protein (α-1-antitrypsin) used to treat emphysema.

C. Golden rice - Rich in vitamin-A: Golden rice is a genetically modified variety of rice that contains increased levels of beta-carotene, a precursor of vitamin A.

D. Bt cotton - Cry protein: Bt cotton is a genetically modified cotton variety that produces a toxin called Cry protein, which is toxic to certain insects, providing the cotton plant with built-in insect resistance.