What is the most suitable condition for the ammonolysis of an alkyl halide? |
273K, open tube 273K, sealed tube 373K, open tube 373K, sealed tube |
373K, sealed tube |
The cleavage of the C-X bond,(X= Cl, Br, I) of the alkyl halide by a nucleophile takes place under high pressure and temperature. Thus, the ammonolysis is carried out in a sealed tube at about 100°C. |