Match List-I with List-II
| List-I Disorders | List-II Features |
|---|---|
| (A) Colour Blindness | (I) 45 with 'XO' |
| (B) Haemophilia | (II) Trisomy of 21 |
| (C) Down's Syndrome | (III) Mutation of certain genes on 'X' chromosome |
| (D) Turner's Syndrome | (IV) Protein involved in clotting of blood |
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 3
The correct answer is Option (3) → (A)-(III), (B)-(IV), (C)-(II), (D)-(I)
(A) Colour Blindness — this matches (III) Mutation of certain genes on ‘X’ chromosome. Colour blindness is a sex-linked recessive disorder. A mutation in certain genes on the X chromosome causes a defect in the red or green cones of the eye. A male has only one X, so it shows far more often in males.
(B) Haemophilia — this matches (IV) Protein involved in clotting of blood. Haemophilia is also sex-linked recessive. A single protein in the chain of proteins that clot the blood is affected, so even a small cut keeps bleeding.
(C) Down’s Syndrome — this matches (II) Trisomy of 21. The person has an extra copy of chromosome 21, three in place of two. The person is short, with a small round head and a furrowed tongue, and mental development is slow.
(D) Turner’s Syndrome — this matches (I) 45 with ‘XO’. One X chromosome is missing, so the female has 45 chromosomes (44 + XO). Such females are sterile, as their ovaries are rudimentary.
Note: The same question was also asked in CUET (UG) 2025 on 03-06-2025 (Slot 1).