The similarities between sickle-cell anaemia and thalassemia are: (A) Both are autosome linked recessive disease Choose the correct answer from the options given below: |
(A), (B) and (D) only (A), (B) and (C) only (A), (B), (C) and (D) (B), (C) and (D) only |
(A), (B) and (C) only |
The correct answer is Option (2) → (A), (B) and (C) only Both are autosome-linked recessive blood disease transmitted from parents to the offspring when both the partners are unaffected carrier for the gene (or heterozygous . Sickle-cell anaemia : This is an autosome linked recessive trait that can be transmitted from parents to the offspring when both the partners are carrier for the gene (or heterozygous). The disease is controlled by a single pair of allele, HbA and HbS. Thalassemia : This is also an autosome-linked recessive blood disease transmitted from parents to the offspring when both the partners are unaffected carrier for the gene (or heterozygous). The defect could be due to either mutation or deletion which ultimately results in reduced rate of synthesis of one of the globin chains (α and β chains) that make up haemoglobin. |