Select the option that is related to the fifth letter-cluster in the same way as the second letter-cluster is related to the first letter-cluster and the fourth letter-cluster is related to the third letter-cluster.

STYE : UVAE :: ELSE : ENUE :: MINE : ?

OIPE

Logic here is :

Add 2 in each Consonant and Vowel remains same .

STYE : UVAE

S(19) + 2 = (21)U , T(20) + 2 = (22)V , Y(25) + 2 = (1)A , E(5) = E(5)

& ELSE : ENUE 

E(5) = (5)E , L(12) + 2 = (14)N , S(19) + 2 = (21)U , E(5) = (5)E

Similarly ,

MINE : ?

M(13) + 2 = (15)O , I(9) = I(9) , N(14) + 2 = (16)P , E(5) = (5)E

OIPE  ,is correct answer .