What negative effects can too much fluoride in drinking water have on health?

Fluorosis

The correct answer is Option (4) - Fluorosis

Excess amounts of fluoride ions in drinking water can cause dental fluorosis, skeletal fluorosis, arthritis, bone damage, osteoporosis, muscular damage, fatigue, joint-related problems, and chronicle issues.

Exposure to high concentrations of fluoride during childhood, when teeth are developing, can result in mild dental fluorosis.

There will be tiny white streaks or specks in the enamel of the tooth. This does not affect the health of the teeth, but the discoloration may be noticeable.