Arrange the following events in correct sequence :
(A) Virus infects macrophages
(B) Viral DNA is produced by reverse transcriptase
(C) Viral DNA incorporates into host genome
(D) Viral RNA is introduced into macrophages
(E) New viruses are produced
Choose the correct answer from the options given below :
Answer & explanation
Correct answer: option 2
The correct answer is Option (2) → (A), (D), (B), (C), (E)
HIV first infects macrophages (A); its RNA enters the cell (D); reverse transcriptase makes viral DNA (B); the DNA joins the host genome (C); new viruses are then made (E).
NCERT Extract:
AIDS – “… After getting into the body of the person, the virus enters into macrophages where RNA genome of the virus replicates to form viral DNA with the help of the enzyme reverse transcriptase. This viral DNA gets incorporated into host cell’s DNA and directs the infected cells to produce virus particles (Figure 7.6).”