Target Exam

CUET

Subject

Biology

Chapter

Molecular Basis of Inheritance

Question:

Match List-I with List-II :

List-I List-II
Structures Characteristics
(A) Heterochromatin (I) A set of positively charged basic proteins
(B) Nucleosomes (II) Densely packed and inactive genetic material
(C) Histones (III) Transcriptionally active genetic material
(D) Euchromatin (IV) DNA is wrapped around the histone octamer to form this structure

Choose the correct answer from the options given below:

Options:

(A)- (II), (B)- (IV), (C)- (I), (D)- (III)

(A)- (I), (B)- (III), (C)- (II), (D)- (IV)

(A)- (I), (B)- (II), (C)- (IV), (D)- (III)

(A)- (III), (B)- (IV), (C)- (I), (D)- (II)

Correct Answer:

(A)- (II), (B)- (IV), (C)- (I), (D)- (III)

Explanation:

The correct answer is Option (1) - (A)- (II), (B)- (IV), (C)- (I), (D)- (III)

List-I List-II
Structures Characteristics
(A) Heterochromatin (II) Densely packed and inactive genetic material
(B) Nucleosomes (IV) DNA is wrapped around the histone octamer to form this structure
(C) Histones (I) A set of positively charged basic proteins
(D) Euchromatin (III) Transcriptionally active genetic material

In a typical nucleus, some region of chromatin are loosely packed (and stains light) and are referred to as euchromatin. The chromatin that is more densely packed and stains dark are called as Heterochromatin. Euchromatin is said to be transcriptionally active chromatin, whereas heterochromatin is inactive. 

In eukaryotes, there is a set of positively charged, basic proteins called histones. A protein acquires charge depending upon the abundance of amino acids residues with charged side chains. Histones are rich in the basic amino acid residues lysine and arginine. Both the amino acid residues carry positive charges in their side chains. Histones are organised to form a unit of eight molecules called histone octamer.

The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome . A typical nucleosome contains 200 bp of DNA helix. A nucleosome consists of nine histone proteins: a core histone octamer—comprising two copies each of H2A, H2B, H3, and H4—and a single linker histone, H1. The linker histone attaches to the DNA segment outside the core particle, playing a key role in chromatin compaction.