The most appropriate antonym of the word "insidious" is sincere.
- Insidious means "proceeding in a gradual, subtle, or stealthy way, especially in order to achieve a harmful or destructive purpose."
- Sincere means "free from pretense or deception; honest."
The other words do not have the opposite meaning of "insidious."
- Treacherous means "betraying trust or confidence in a treacherous way."
- Astute means "having or showing keen insight or discernment."
- Stealthy means "moving or acting in a cautious or surreptitious way, so as to avoid detection."
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