In which phase of cell cycle does replication of DNA take place?

S phase

The correct answer is Option (3) → S phase

The S phase (Synthesis phase) of the cell cycle is the phase during which DNA replication occurs. During this phase, the cell duplicates its genetic material to ensure that each daughter cell receives a complete set of chromosomes after cell division. The replication of DNA and cell division cycle should be highly coordinated. A failure in cell division after DNA replication results into polyploidy (a chromosomal anomaly)