Managing diabetes is possible by administering insulin periodically. Insulin used for diabetes was earlier extracted from pancreas of slaughtered cattle and pigs. However, this insulin caused some people to develop allergies and other types of reactions. In mammals, including humans, insulin is synthesized as a prohormone and is later converted to insulin.

Which of the following happens during the maturation of insulin?

C peptide is added to proinsulin. B peptide is added to proinsulin. C peptide is removed from proinsulin. B peptide is removed from proinsulin.

C peptide is removed from proinsulin.

In mammals, insulin is secreted as pro-hormone which contains an extra peptide C which is not present in mature insulin.This C peptide is not present in the mature insulin and is removed during maturation into insulin.