Select the most appropriate option to fill in the blank.

A ______ girl is missing from my Colony.

little

The most appropriate option to fill in the blank is little.

• Less means a smaller amount or quantity than something else.
• So means to such an extent or degree.
• Little means small in size, amount, or quantity.
• Few means not many.

In the sentence, the speaker is saying that there is a small girl missing from the colony. Therefore, the most appropriate word is little.