Practicing Success
To convert ethanamide into Methanamine which of the following reagents can be used? |
LiAlH4, H2O H2/Ni, Na(Hg)/C2H5OH Br2 and NaOH Sn and HCl |
Br2 and NaOH |
Hoffmann developed a method for preparation of primary amines by treating an amide with bromine in an aqueous or ethanolic solution of sodium hydroxide. In this degradation reaction, migration of an alkyl or aryl group takes place from carbonyl carbon of the amide to the nitrogen atom. The amine so formed contains one carbon less than that present in the amide. |