Which type of leukocytes can phagocytose and destroy microbes?

Macrophages

 The correct answer is Option (3)- Macrophages

Macrophages are a type of leukocyte (white blood cell) that play a crucial role in innate immunity. They are specialized phagocytic cells that can engulf and destroy microbes, foreign particles, and cellular debris. Macrophages are found in various tissues throughout the body, such as the liver, spleen, lymph nodes, and lungs.
When pathogens or foreign substances enter the body, macrophages recognize them through specific receptors on their cell surface. Once recognized, macrophages extend their cellular projections called pseudopodia to surround and engulf the foreign material. This process is known as phagocytosis. Once inside the macrophage, the engulfed material is broken down and destroyed by enzymes and other antimicrobial substances present within the cell.
In addition to their phagocytic function, macrophages also play a role in antigen presentation. They can process and present antigens from engulfed pathogens to other immune cells, such as T-lymphocytes, to initiate an adaptive immune response.
Overall, macrophages are an essential component of the innate immune system and are responsible for recognizing, engulfing, and destroying microbes, contributing to the body's defense against infections.