Target Exam

CUET

Subject

Biology

Chapter

Principles of Inheritance and Variation

Question:

The genetic disorder caused due to presence of an additional copy of the chromosome number 21 is:

Options:

Down's syndrome

Klinefelter syndrome

Turner's syndrome

Haemophilia

Correct Answer:

Down's syndrome

Explanation:

The correct answer is Option (1) – Down's syndrome

Down’s Syndrome : The cause of this genetic disorder is the presence of an additional copy of the chromosome number 21 (trisomy of 21).

This disorder was first described by Langdon Down (1866). The affected individual is short statured with small round head, furrowed tongue and partially open mouth.

Palm is broad with characteristic palm crease. Physical, psychomotor and mental development is retarded.