The most appropriate antonym of the word "persist" is cease.
- Persist means "to continue in something despite opposition, obstacles, or discouragement."
- Cease means "to stop or bring to an end."
The other words do not have the opposite meaning of "persist."
- Remain means "to stay in a particular place or condition."
- Continue means "to go on or keep going in a particular way or direction."
- Insist means "to demand or request something in a firm or forceful way."
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