Eli Lilly company used __________ to produce the recombinant insulin.
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → E. coli
Eli Lilly made two DNA sequences, one for chain A and one for chain B of human insulin, and put them into plasmids of E. coli. The bacteria made the two chains separately. The chains were then taken out and joined by disulphide bonds to give human insulin.
(1) E. coli — Correct. It was the host that made the insulin chains.
(2) Aspergillus niger — Incorrect. This fungus is used for the industrial production of citric acid.
(3) Saccharomyces cerevisiae — Incorrect. This is brewer’s yeast. It is used for bread-making and for producing ethanol.
(4) Agrobacterium tumefaciens — Incorrect. This bacterium is used to carry genes into plant cells. It was not used for insulin.
NCERT Extract:
Genetically Engineered Insulin – …
