Match Column 1 with Column 2:
| Column 1 (Bioactive substance) | Column 2 (Role) |
| A. Statins | i. Removal of oil stains |
| B. Cyclosporin A | ii. Removal of clots from blood vessels |
| C. Streptokinase | iii. Lowering of blood cholesterol |
| D. Lipase | iv. Immuno-suppressive agent |
Answer & explanation
Correct answer: option 4
The correct answer is Option (4) → A-iii, B-iv, C-ii, D-i
(A) Statins — this matches (iii) Lowering of blood cholesterol. Statins come from the yeast Monascus purpureus. They block the enzyme that makes cholesterol, so blood cholesterol falls.
(B) Cyclosporin A — this matches (iv) Immuno-suppressive agent. It is made by the fungus Trichoderma polysporum and is given to organ-transplant patients to suppress the immune response.
(C) Streptokinase — this matches (ii) Removal of clots from blood vessels. It is made by the bacterium Streptococcus and is used as a ‘clot buster’ after a heart attack.
(D) Lipase — this matches (i) Removal of oil stains. Lipases digest fats and oils, so they are added to detergents to remove oily stains from the laundry.
NCERT Extract:
Chemicals, Enzymes and other Bioactive Molecules – “… Lipases are used in detergent formulations and are helpful in removing oily stains from the laundry. … Streptokinase produced by the bacterium Streptococcus and modified by genetic engineering is used as a ‘clot buster’ for removing clots from the blood vessels of patients who have undergone myocardial infarction leading to heart attack. Another bioactive molecule, cyclosporin A, that is used as an immunosuppressive agent in organ-transplant patients, is produced by the fungus Trichoderma polysporum. Statins produced by the yeast Monascus purpureus have been commercialised as blood-cholesterol lowering agents.”