Which among the following is responsible to damage nervous system and liver (cirrhosis) ?

Alcohol

The correct answer is Option (4) → Alcohol

Alcohol is readily absorbed from the digestive tract, and up to 98% is metabolised in the liver. Each liver cell contains three pathways for alcohol metabolism. All of these result in the production of a highly toxic metabolite which can contribute to liver cell damage. With regular alcohol use, the regenerative ability of liver cells may be inhibited and lead to sustained liver damage. Long term heavy alcohol use may lead to fat accumulation in the liver, which may progress to alcoholic hepatitis, or liver cirrhosis.

The use of alcohol during adolescence may also have long-term effects. It could lead to heavy drinking in adulthood. The chronic use of drugs and alcohol damages nervous system and liver (cirrhosis). The use of drugs and alcohol during pregnancy is also known to adversely affect the foetus.