CUET Preparation Today
Case: Read the following passage and answer accordingly Amines are prepared mainly by the reduction of nitro compounds. Alkyl or benzyl halide on reaction with an ethanolic solution of ammonia undergoes nucleophilic substitution reaction in which the halogen atom is replaced by an amino group. Amines are prepared from Phthalimide. Treating an amide with bromine in an aqueous or ethanolic solution of sodium hydroxide result in amines. |
| Secondary amines could be prepared by; |
Hoffmann bromamide reaction Gabriel synthesis Oxidation of isonitriles Reduction of isonitriles |
| Reduction of isonitriles |
| Secondary amines are formed when isonitriles are reduced with hydrogen in pressure of Pt catalyst. |
