Statement I: An organ transplant patient is administered a regular dose of cyclosporin-A.
Statement II: Cyclosporin-A is an immunosuppressant agent.
Answer & explanation
Correct answer: option 3
The correct answer is Option (3) → Both Statement I and Statement II are correct.
After an organ transplant, the body’s immune system may attack the new organ as foreign tissue and reject it. Drugs that suppress the immune response, called immunosuppressants, are given to prevent this. Cyclosporin A is one such bioactive molecule made by a microbe, the fungus Trichoderma polysporum.
Statement I: An organ transplant patient is administered a regular dose of cyclosporin-A. — True. Cyclosporin A is used in organ-transplant patients to keep the immune system from rejecting the transplanted organ.
Statement II: Cyclosporin-A is an immunosuppressant agent. — True. NCERT describes cyclosporin A as an immunosuppressive agent, that is, it lowers the immune response.
Both statements are correct.
NCERT Extract:
Chemicals, Enzymes and other Bioactive Molecules – “Another bioactive molecule, cyclosporin A, that is used as an immunosuppressive agent in organ-transplant patients, is produced by the fungus Trichoderma polysporum. Statins produced by the yeast Monascus purpureus have been commercialised as blood-cholesterol lowering agents. It acts by competitively inhibiting the enzyme responsible for synthesis of cholesterol.”