Arrange the following steps of translation in the correct sequence:
(A) Binding of tRNA to mRNA
(B) Formation of peptide bond
(C) Movement of ribosomes along with mRNA
(D) Termination and release of the complete polypeptide
Choose the correct answer from the options given below:
Answer & explanation
Correct answer: option 1
The correct answer is Option (1) → (A), (B), (C), (D)
(A) Binding of tRNA to mRNA — this comes first. A tRNA that carries its amino acid pairs, through its anticodon, with the codon on the mRNA. Translation starts at the start codon AUG.
(B) Formation of peptide bond — this comes second. When two tRNAs sit side by side on the ribosome, a peptide bond joins their amino acids.
(C) Movement of ribosomes along with mRNA — this comes third. The ribosome moves by one codon, so the next tRNA can bind. Steps (A) to (C) repeat, and the chain grows one amino acid at a time.
(D) Termination and release of the complete polypeptide — this comes last. When the ribosome reaches a stop codon, a release factor binds to it. Translation ends and the finished polypeptide is released.