Practicing Success
The reaction on an alkyl halide with RCOOAg produces |
Ester Aldehyde Ether Ketone |
Ester |
The reaction of an alkyl halide with RCOOAg produces an ester. The reaction is called the Claisen-Schmidt condensation. It is a nucleophilic acyl substitution reaction that occurs between an alkyl halide and an ester in the presence of a base. The base, in this case RCOOAg, acts as a nucleophile and attacks the alkyl halide, displacing the halide ion. The resulting intermediate then reacts with the ester to form an ester. The reaction is shown below: Where R and R' are alkyl groups, X is a halide, and AgX is a silver halide. The Claisen-Schmidt condensation is a versatile reaction that can be used to synthesize a variety of esters. It is also used in the production of perfumes and flavors. |